Physical Education
Ladan Hosseini Abrishami; Seyed Mahmud Hejazi; Amir Rashid Lamir
Volume 27, Issue 5 , November and December 2020, , Pages 710-718
Abstract
Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials ...
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Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials and Methods: 42 men with heart failure were selected by sampling method as volunteers and were divided into three equal groups (14 subjects) continuous aerobic, intermittent aerobic exercises and control groups. Continuous training (45-70% of Maximum Heart Rate) and intermittent training (45-80% of MHR with 5-10 minutes rest between each period) were done for 8 weeks (three days a week). Fasting blood samples were taken from all subjects before and after eight weeks of aerobic exercise and adhesion molecules were measured by ELISA method. Data were analyzed by ANCOVA at significance levels of P<0.05.
Results: Comparison of the groups with covariance analysis showed that the levels of E-selectin (P=0.002) and P-selectin (P=0.022) levels was significant in all three groups. The Bonferroni test showed, There was a significant difference between the intermittent and control (P=0.005) and between continuous and control groups (P=0.006) at the level of Eselectin and the intermittent aerobic and control groups (P=0.032) at Pselectin level, However, there was no significant change despite a decrease between the control and continuing aerobic (P=0.083) in Pselecteine. Also, there was no significant difference in the studied variables in both intermittent and continuous aerobic groups.
Conclusion: Aerobic exercise with reducing levels of adhesion molecules may play an important role in the prevention and control of cardiovascular diseases in men with heart failure.
Physical Education
Ladan Hosseini Abrishami; Seyed Mahmud Hejazi; Amir Rashdlamir; Rambod Khajei
Volume 26, Issue 4 , November and December 2019, , Pages 495-504
Abstract
IntroductionEvidence showed that adhesion molecules and inflammatory factors play an important role in the pathogenesis of atherosclerosis.The purpose of this study was to evaluate the effect of eight weeks of continuous and periodic aerobic exercise on the serum level of C-reactive protein and some ...
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IntroductionEvidence showed that adhesion molecules and inflammatory factors play an important role in the pathogenesis of atherosclerosis.The purpose of this study was to evaluate the effect of eight weeks of continuous and periodic aerobic exercise on the serum level of C-reactive protein and some adhesive molecules in men with heart failure. Materials and MethodsIn this study, 42 middle-aged men with heart failure were purposeful and randomly divided into three equal groups(14 subjects): continuous aerobic exercise, periodic aerobic exercise and control groups. Continuous training(45-70% of Maximum Heart Rate) and periodic exercise (45-80% of MHR with 5-10 minutes rest between each period) were done for 8 weeks(three days a week). Before and after exercise, blood samples were taken from three groups, ELISA method was used. Data were analyzed using SPSS (20 version) at a significant level of P≤0.05. ResultsAfter eight weeks of training, the level of C-reactive protein, adhesion molecule -1 and vascular adhesion molecule -1 had a significant decrease in the two training groups(P ≤ 0.05). but no significant difference was observed in the control group. There was a significant difference between the levels of hs-CRP(P = 0.023) and VCAM-1(P = 0.0001) in all three groups, but there was not a significant difference in ICAM-1 level(P = 0.17).ConclusionAerobic exercise by decreasing the levels of hs-CRP and VCAM-1 may play an important role in the prevention and control of cardiovascular disease in men with heart failure.
Physical Education
Mohammad Hoseinzadeh; Amir Rashidlamir; Seyed Mahmud Hejazi
Volume 25, Issue 5 , November and December 2018, , Pages 629-637
Abstract
Background and purpose: Fibronectin transmembrane type III domain-containing protein 5 (FNDC5) is a characteristic factor in distinguishing skeletal muscle cells. Since the productive effects of regular exercise are conveyed through the skeletal muscle, this study aims to compare the effects of progressive ...
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Background and purpose: Fibronectin transmembrane type III domain-containing protein 5 (FNDC5) is a characteristic factor in distinguishing skeletal muscle cells. Since the productive effects of regular exercise are conveyed through the skeletal muscle, this study aims to compare the effects of progressive endurance and resistance training on FNDC5 gene expression in male rats’ gastrocnemius muscles.Materials and Methods: 15 male rats were randomly assigned to three equal groups of: control, endurance training and resistance training. The endurance group performed 8 weeks of training on the treadmill. The resistance group did their exercises for eight weeks on a three-session-per-week basis on a one-meter-high ladder with 85○ slope. All subjects were anesthetized 72 hours after the experiment finished and the gastrocnemius removed. The level of FNDC5 expression was measured through real-time PCR method and one-way ANOVA applied to analyze the data. Level of significance was set to P≥0.05.Results: One-way ANOVA showed a significant difference in FNDC5 expression among the groups (P=0.001, F=31.791). A subsequent Tukey test application showed FNDC5 gene expression of the gastrocnemius muscle was significantly higher in the resistance and endurance training groups than in the control group (P